Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255582 | 0.92 | MCHR1 (0.69) | MCHR1DGAT1SIGMAR1NPY5RCHRM4 | |
| SCHEMBL7254624 | 0.92 | DGAT1 (0.58) | MCHR1DGAT1SIGMAR1 | |
| SCHEMBL7258185 | 0.91 | MCHR1 (0.68) | MCHR1DGAT1SIGMAR1NPY5RCHRM4 | |
| SCHEMBL7258523 | 0.91 | MCHR1 (0.65) | MCHR1DGAT1SIGMAR1CHRM4MCHR2 | |
| SCHEMBL7254619 | 0.90 | MCHR1 (0.66) | MCHR1DGAT1SIGMAR1CHRM4EPHX2 | |
| SCHEMBL7254555 | 0.86 | MCHR1 (0.67) | MCHR1GAADGAT1SIGMAR1NPY5R | |
| SCHEMBL7255916 | 0.85 | MCHR1 (0.61) | MCHR1DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7258373 | 0.85 | MCHR1 (0.60) | MCHR1DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7255884 | 0.84 | MCHR1 (0.59) | MCHR1DGAT1SIGMAR1CHRM4MCHR2 | |
| SCHEMBL7258396 | 0.84 | DGAT1 (0.60) | MCHR1LMNASMN1; SMN2DGAT1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087046-A1 | NOVEL AMINOTETRALINE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |