Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 7/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.51 |
| ▸ | MCHR2 | Q969V1 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255582 | 0.99 | MCHR1 (0.69) | MCHR1MEN1KMT2AALDH1A1GLA | |
| SCHEMBL7254689 | 0.91 | MCHR1 (0.70) | MCHR1DGAT1MCHR2SIGMAR1CHRM4 | |
| SCHEMBL7258396 | 0.91 | DGAT1 (0.60) | MCHR1MEN1KMT2AALDH1A1DGAT1 | |
| SCHEMBL7254619 | 0.91 | MCHR1 (0.66) | MCHR1ALDH1A1DGAT1MCHR2SIGMAR1 | |
| SCHEMBL7258523 | 0.90 | MCHR1 (0.65) | MCHR1ALDH1A1DGAT1MCHR2SIGMAR1 | |
| SCHEMBL7254555 | 0.85 | MCHR1 (0.67) | MCHR1MEN1KMT2AALDH1A1DGAT1 | |
| SCHEMBL7255884 | 0.85 | MCHR1 (0.59) | MCHR1DGAT1MCHR2SIGMAR1CHRM4 | |
| SCHEMBL7255916 | 0.84 | MCHR1 (0.61) | MCHR1DGAT1SIGMAR1NPC1RAB9A | |
| SCHEMBL7258373 | 0.84 | MCHR1 (0.60) | MCHR1DGAT1SIGMAR1CHRM4 | |
| SCHEMBL7254582 | 0.83 | MCHR1 (0.57) | MCHR1DGAT1MCHR2SIGMAR1CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003087046-A1 | NOVEL AMINOTETRALINE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |