Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259712 | 0.71 | PARP1 (0.47) | FBP1MAPTLMNAKDM4ENPC1 | |
| SCHEMBL7717951 | 0.70 | GAA (0.50) | MAPTGAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL6519093 | 0.70 | GRM5 (0.30) | — | |
| SCHEMBL221991 | 0.70 | MAPT (0.63) | MAPTLMNAMAPK1GAACYP1A2 | |
| SCHEMBL7259069 | 0.67 | ALDH1A1 (0.53) | FBP1MAPTGAACYP1A2CYP3A4 | |
| SCHEMBL5485539 | 0.67 | NSD2 (0.40) | MAPTNSD2CASP6GAACYP3A4 | |
| SCHEMBL7717955 | 0.65 | NPC1 (0.50) | MAPTNSD2CASP6GAAKDM4E | |
| SCHEMBL29949338 | 0.64 | NSD2 (0.41) | NSD2CASP6CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL26965532 | 0.64 | NSD2 (0.41) | NSD2CASP6CYP3A4ALDH1A1ALOX15 | |
| SCHEMBL28499395 | 0.62 | ALDH1A1 (0.62) | FBP1MAPTLMNAGAATLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057667-A2 | STRAPPED AND MODIFIED BIS (BENZIMIDAZOLE) DIAMIDES FOR ASYMMETRIC CATALYSTS AND OTHER APPLICATIONS | THE OHIO STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2003-07-17 | — | — | WO | disclosed |
| US-6376664-B1 | DETECTORS, CATALYST | THE OHIO STATE UNIVERSITY | 2002-04-23 | — | — | US | disclosed |