Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MGAM | O43451 | 5/20 | 0.39 |
| ▸ | SI | P14410 | 5/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.39 |
| ▸ | PARP1 | P09874 | 5/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718401 | 0.80 | GAA (0.62) | GAAKDM4EALDH1A1MAPTMGAM | |
| SCHEMBL7717955 | 0.80 | NPC1 (0.50) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9718865 | 0.77 | GAA (0.65) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL9045167 | 0.70 | PARP1 (0.60) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL7717958 | 0.70 | GAA (0.55) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL5485539 | 0.68 | NSD2 (0.40) | GAASMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL218892 | 0.68 | NPC1 (1.00) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL29424535 | 0.68 | NPC1 (1.00) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL913494 | 0.66 | PDE5A (0.68) | GAASMN1; SMN2NPC1RAB9AHPGD | |
| SCHEMBL17133398 | 0.66 | MGAM (0.56) | HPGDKDM4EALDH1A1MAPTMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376664-B1 | DETECTORS, CATALYST | THE OHIO STATE UNIVERSITY | 2002-04-23 | — | — | US | disclosed |