Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255113 | 1.00 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1UPP1NPC1TDP1 | |
| SCHEMBL7260757 | 0.86 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1UPP1NPC1KDM4E | |
| SCHEMBL7255873 | 0.84 | ALDH1A1 (0.38) | ALDH1A1UPP1KDM4ELMNAMAPT | |
| SCHEMBL7256071 | 0.82 | ALDH1A1 (0.32) | ALDH1A1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL2107018 | 0.80 | SMN1; SMN2 (0.36) | ALDH1A1UPP1TDP1KDM4EKMT2A | |
| SCHEMBL7254871 | 0.79 | ALDH1A1 (0.32) | ALDH1A1TDP1KMT2ASMN1; SMN2 | |
| SCHEMBL7758263 | 0.78 | TP53 (0.36) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL7758268 | 0.78 | TP53 (0.36) | ALDH1A1KDM4ELMNAMAPTHTT | |
| SCHEMBL5199239 | 0.78 | UPP1 (0.44) | UPP1HTT | |
| SCHEMBL7254857 | 0.78 | ALDH1A1 (0.37) | ALDH1A1UPP1NPC1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057677-A1 | ANTI-RETROVIRAL 5,6-DISUBSTITUTED ACYCLOPYRIMIDINE NUCLEOSIDE DERIVATIVES | SYDDANSK UNIVERSITET (DK) | 2003-07-17 | — | — | WO | disclosed |