Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258618 | 0.77 | ALDH1A1 (0.44) | ALDH1A1KMT2ARAB9AMEN1TSHR | |
| SCHEMBL30729287 | 0.74 | POLB (0.53) | ALDH1A1KMT2ATSHRL3MBTL1MAPT | |
| SCHEMBL4913727 | 0.71 | L3MBTL1 (0.48) | ALDH1A1KMT2ARAB9AMEN1TSHR | |
| SCHEMBL7038689 | 0.70 | KDM4E (0.75) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL7259626 | 0.69 | ALDH1A1 (0.43) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL3059132 | 0.69 | ALDH1A1 (0.62) | ALDH1A1KMT2ARAB9AMEN1KDM4E | |
| SCHEMBL2937870 | 0.67 | TSHR (0.63) | ALDH1A1KMT2ATSHRSMN1; SMN2KDM4E | |
| SCHEMBL19512864 | 0.67 | TSHR (0.63) | ALDH1A1KMT2ATSHRSMN1; SMN2KDM4E | |
| SCHEMBL17821433 | 0.67 | MYC (0.77) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 | |
| SCHEMBL7255171 | 0.67 | ALDH1A1 (0.40) | ALDH1A1KMT2ARAB9AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003099812-A1 | PHENYL-FURAN OR PHENYL-THIOPHENE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINE | PIERRE FABRE MEDICAMENT (FR) | 2003-12-04 | — | — | WO | disclosed |