Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LTA4H | P09960 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MASP2 | O00187 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255193 | 0.86 | F2 (0.39) | MDM2KDM4EMASP2F2CYP2C9 | |
| SCHEMBL7254368 | 0.70 | F2 (0.43) | MEN1KMT2AKDM4EMASP2F2 | |
| SCHEMBL7254370 | 0.70 | F2 (0.43) | MEN1KMT2AKDM4EMASP2F2 | |
| SCHEMBL7255198 | 0.68 | F2 (0.46) | MASP2F2CYP2C9PTGER1 | |
| SCHEMBL7258197 | 0.68 | MEN1 (0.45) | MEN1KMT2AKDM4ETSHRLMNA | |
| SCHEMBL7254246 | 0.63 | MEN1 (0.41) | MEN1KMT2AKDM4ETSHRLMNA | |
| SCHEMBL7254244 | 0.63 | MEN1 (0.41) | MEN1KMT2AKDM4ETSHRLMNA | |
| SCHEMBL5855156 | 0.60 | MEN1 (0.47) | MEN1KMT2AKDM4ETSHRLMNA | |
| SCHEMBL5855166 | 0.60 | MEN1 (0.47) | MEN1KMT2AKDM4ETSHRLMNA | |
| SCHEMBL5855369 | 0.59 | MEN1 (0.46) | MEN1KMT2AKDM4ETSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011222-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2003-02-13 | — | — | WO | disclosed |