Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MASP2 | O00187 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7255189 | 0.86 | MDM2 (0.33) | F2PTGER1CYP2C9MASP2MDM2 | |
| SCHEMBL7254368 | 0.83 | F2 (0.43) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL7254370 | 0.83 | F2 (0.43) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL7255198 | 0.80 | F2 (0.46) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL7259758 | 0.70 | F2 (0.36) | F2PRSS1PRSS2PRSS3PTGER1 | |
| SCHEMBL7258197 | 0.66 | MEN1 (0.45) | CYP2C9KDM4E | |
| SCHEMBL7254334 | 0.65 | IDO1 (0.44) | PTGER1CYP2C9KDM4E | |
| SCHEMBL30933809 | 0.65 | CYP1A2 (0.56) | — | |
| SCHEMBL7255214 | 0.65 | IDO1 (0.43) | PTGER1CYP2C9KDM4E | |
| SCHEMBL7257945 | 0.65 | IDO1 (0.43) | PTGER1CYP2C9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003011222-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2003-02-13 | — | — | WO | disclosed |