Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399676 | 0.84 | TSHR (0.79) | TSHRKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7843044 | 0.84 | PTGDR2 (0.59) | TSHRKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL7848040 | 0.83 | PTGDR2 (0.54) | TSHRKDM4EPTGDR2GLAL3MBTL1 | |
| SCHEMBL17897050 | 0.83 | PTGDR2 (0.54) | TSHRKDM4EPTGDR2GLAL3MBTL1 | |
| SCHEMBL16952087 | 0.80 | MAPT (0.45) | TSHRKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL320418 | 0.80 | PTGDR2 (0.66) | TSHRKDM4EPTGDR2GLAL3MBTL1 | |
| SCHEMBL4576444 | 0.79 | L3MBTL1 (0.66) | TSHRKDM4EALDH1A1HPGDPTGDR2 | |
| SCHEMBL16342279 | 0.79 | PTGDR2 (0.60) | TSHRKDM4EPTGDR2GLAL3MBTL1 | |
| SCHEMBL3064143 | 0.78 | TSHR (0.70) | TSHRKDM4EALDH1A1HSD17B10PTGDR2 | |
| SCHEMBL14363092 | 0.78 | L3MBTL1 (0.67) | TSHRKDM4EALDH1A1PTGDR2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003101406-A1 | HOMO-CAMPTOTHECIN DERIVATIVES | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2003-12-11 | — | — | WO | disclosed |