Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 3/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7251419 | 0.94 | MEN1 (0.42) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7030722 | 0.91 | F10 (0.40) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7032387 | 0.90 | F10 (0.40) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7037813 | 0.90 | ITGB3 (0.49) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7037933 | 0.89 | ITGB3 (0.46) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7037677 | 0.89 | ITGB3 (0.45) | F10MEN1POLBKMT2AITGB3 | |
| SCHEMBL7037166 | 0.89 | PLAU (0.43) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7037936 | 0.89 | F10 (0.39) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7039155 | 0.89 | F10 (0.43) | F10PLAUF2PLATMEN1 | |
| SCHEMBL7036018 | 0.88 | F10 (0.42) | F10PLAUF2PLATMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586187-B1 | 2-benzyloxycarbonylamino-3-(2-(4-(2-(3-benzylureido)-ethyl) -piperazin-1-yl)acetylamino)-propionic acid, for example; method of synthesis using Wang resins; various uses including anticancer, antiinflammatory and antiviral agents | WYETH | 2003-07-01 | — | — | US | disclosed |
| WO-2000061545-A1 | METHODS FOR SOLID PHASE COMBINATORIAL SYNTHESIS OF INTEGRIN INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-10-19 | — | — | WO | disclosed |