SCHEMBL7037166

SCHEMBL7037166

CCOC(=O)N[C@@H](CNC(=O)c1ccc(OCCNC(=N)N)cc1O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLAU P00749 2/20 0.43
F10 P00742 2/20 0.43
F2 P00734 1/20 0.43
PLAT P00750 1/20 0.43
ITGB3 P05106 8/20 0.42
ITGAV P06756 3/20 0.42
MEN1 O00255 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
KLKB1 P03952 1/20 0.38
MAPK1 P28482 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
ITGA2B P08514 6/20 0.37
EGLN2 Q96KS0 1/20 0.36
EGLN1 Q9GZT9 1/20 0.36
HPGD P15428 2/20 0.36
TAS1R3 Q7RTX0 1/20 0.36
TAS1R1 Q7RTX1 1/20 0.36
ALDH1A1 P00352 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7038291 0.94 ITGB3 (0.41) PLAUF10F2PLATITGB3
SCHEMBL7035668 0.93 ITGB3 (0.43) PLAUF10F2PLATITGB3
SCHEMBL7030722 0.92 F10 (0.40) PLAUF10F2PLATITGB3
SCHEMBL7251419 0.91 MEN1 (0.42) PLAUF10F2PLATITGB3
SCHEMBL7032391 0.91 ITGB3 (0.43) PLAUF10F2PLATITGB3
SCHEMBL7031295 0.90 ITGB3 (0.40) PLAUF10F2PLATITGB3
SCHEMBL7034815 0.89 ITGB3 (0.53) ITGB3ITGAVITGA2BEGLN2EGLN1
SCHEMBL7039155 0.89 F10 (0.43) PLAUF10F2PLATITGB3
SCHEMBL7255333 0.89 F10 (0.40) PLAUF10F2PLATITGB3
SCHEMBL7036039 0.89 ITGB3 (0.40) PLAUF10F2PLATITGB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US claimed
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors AMERICAN HOME PRODUCTS CORPORATION (US) 2003-10-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186967-A1 Acylresorcinol derivatives are selective vitronectin receptor inhibitors ASGR1, TEK, APLNR PLAU 2202/4885F10 2695/4885F2 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.