Methane

Methane

SCHEMBL725576

C.O=C1c2ccccc2C(=O)C1c1ccc2ccccc2n1

nearest known ligand 0.96

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 10/20 0.96
NPC1 O15118 9/20 0.96
MAPT P10636 8/20 0.96
SMN1; SMN2 Q16637 7/20 0.96
KMT2A Q03164 6/20 0.96
TP53 P04637 5/20 0.96
MEN1 O00255 5/20 0.96
ALDH1A1 P00352 4/20 0.96
CYP3A4 P08684 3/20 0.96
MAPK1 P28482 2/20 0.96
HIF1A Q16665 1/20 0.96
ESR1 P03372 1/20 0.67
LMNA P02545 2/20 0.43
POLB P06746 2/20 0.43
PTK2B Q14289 1/20 0.42
CYP1A2 P05177 2/20 0.42
NCF1 P14598 1/20 0.42
NOS2 P35228 1/20 0.42
BACE1 P56817 1/20 0.42
HTR2B P41595 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29350835 0.98 RAB9A (1.00) RAB9ANPC1MAPTSMN1; SMN2KMT2A
SCHEMBL42716 0.98 RAB9A (1.00) RAB9ANPC1MAPTSMN1; SMN2KMT2A
SCHEMBL21817022 0.98 RAB9A (1.00) RAB9ANPC1MAPTSMN1; SMN2KMT2A
SCHEMBL7791036 0.96 RAB9A (0.96) RAB9ANPC1MAPTSMN1; SMN2KMT2A
SCHEMBL9513625 0.96 RAB9A (0.96) RAB9ANPC1MAPTSMN1; SMN2KMT2A
Ethyne SCHEMBL6237008 0.95 RAB9A (0.93) RAB9ANPC1MAPTSMN1; SMN2KMT2A
Cyanide SCHEMBL8518292 0.93 RAB9A (0.90) RAB9ANPC1MAPTSMN1; SMN2KMT2A
Bicarbonate SCHEMBL7756326 0.92 RAB9A (0.87) RAB9ANPC1MAPTSMN1; SMN2KMT2A
Phthalimide SCHEMBL5678400 0.89 MAPT (0.82) RAB9ANPC1MAPTSMN1; SMN2KMT2A
SCHEMBL29120606 0.88 ALDH1A1 (0.81) RAB9ANPC1MAPTSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024100226-A1 CLEANING COMPOSITION NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2024-05-16 WO disclosed
EP-3574079-B1 STABLE UNIT DOSE COMPOSITIONS WITH HIGH WATER CONTENT AND STRUCTURED SURFACTANTS HENKEL AG & CO KGAA (DE) 2024-05-01 EP disclosed
US-11873466-B2 Opacified liquid detergent composition comprising a fatty acid/calcium salt mixture HENKEL AG & CO. KGAA (DE) 2024-01-16 US disclosed
EP-3858962-B1 UNIT DOSE DETERGENT PACK INCLUDING A LIQUID DETERGENT COMPOSITION COMPRISING AN ALKYL POLYGLYCOSIDE SURFACTANT HENKEL AG & CO KGAA (DE) 2024-01-03 EP disclosed
US-11788031-B2 Opacified liquid detergent composition comprising a fatty acid/Mg cation/Ca cation mixture and having improved structural stability HENKEL AG & CO. KGAA (DE) 2023-10-17 US disclosed
EP-4237522-A1 OPACIFIED LIQUID DETERGENT COMPOSITION FREE OF A MICROPLASTIC OPACIFIER AND HAVING IMPROVED STRUCTURAL STABILITY Henkel AG & Co. KGaA (DE) 2023-09-06 EP disclosed
EP-4237523-A1 METHOD OF MAKING AN OPACIFIED LIQUID DETERGENT COMPOSITION IN THE ABSENCE OF A MICROPLASTIC OPACIFIER Henkel AG & Co. KGaA (DE) 2023-09-06 EP disclosed
EP-4237524-A1 OPACIFIED LIQUID DETERGENT COMPOSITION THAT IS FREE OF A MICROPLASTIC OPACIFIER Henkel AG & Co. KGaA (DE) 2023-09-06 EP disclosed
US-11674114-B2 Method of making an opacified liquid detergent composition using a divalent cation solution HENKEL AG & CO. KGAA (DE) 2023-06-13 US disclosed
US-11560534-B2 Surfactant compositions for improved transparency of DADMAC-acrylamide co-polymers HENKEL AG & CO. KGAA 2023-01-24 US disclosed
US-20090264335-A1 LAUNDRY TREATMENT COMPOSITIONS CONOPCO INC., D/B/A UNILEVER (US) 2009-10-22 US disclosed
US-7569531-B2 Laundry treatment compositions containing a photostable dye CONOPCO INC. (US) 2009-08-04 US disclosed
EP-1633842-B1 LAUNDRY TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2008-07-23 EP disclosed
EP-1921132-A2 Laundry treatment composition Unilever Plc (GB) 2008-05-14 EP disclosed
WO-2007054238-A1 HYGIENE INDICATOR DEVICE UNILEVER N.V. (NL) 2007-05-18 WO disclosed
US-20060287211-A1 Laundry treatment compositions CONOPCO, INC., D/B/A UNILEVER, A CORPORATION OF NEW YORK 2006-12-21 US disclosed
EP-1633843-A1 LAUNDRY TREATMENT COMPOSITIONS Unilever Plc (GB) 2006-03-15 EP disclosed
EP-1633842-A1 LAUNDRY TREATMENT COMPOSITIONS Unilever Plc (GB) 2006-03-15 EP disclosed
WO-2005003274-A1 LAUNDRY TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2005-01-13 WO disclosed
WO-2005003275-A1 LAUNDRY TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2005-01-13 WO disclosed