SCHEMBL7255779

SCHEMBL7255779

C=C(C)C(=C)C.CC1=Cc2c(-c3ccccc3)cccc2C1[Zr]

nearest known ligand 0.34

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
HTR2B P41595 1/20 0.31
TMEM97 Q5BJF2 1/20 0.31
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30
BCL2L1 Q07817 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CHRNB2 P17787 1/20 0.30
CHRNA4 P43681 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603520 0.91 PDCD1 (0.36) PDCD1CD274HTR2BTMEM97EDNRB
SCHEMBL7861218 0.91 PDCD1 (0.32) PDCD1CD274
Hydrochloric Acid SCHEMBL5695379 0.90 PDCD1 (0.35) PDCD1CD274HTR2BTMEM97EDNRB
Hydrochloric Acid SCHEMBL28723777 0.90 PDCD1 (0.35) PDCD1CD274HTR2BTMEM97EDNRB
Chloromethane SCHEMBL5722647 0.88 PDCD1 (0.34) PDCD1CD274EDNRBEDNRALMNA
SCHEMBL27474790 0.87 ADRA2A (0.35) PDCD1CD274HTR2BTMEM97ALDH1A1
SCHEMBL7862483 0.82
SCHEMBL7855703 0.82 PDCD1 (0.32) PDCD1CD274
SCHEMBL27485116 0.82 EDNRB (0.34) EDNRBEDNRALMNAALDH1A1
SCHEMBL27477931 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030199650-A1 Bridged metal complexes for gas phase polymerizations BP CHEMICALS LIMITED 2003-10-23 US disclosed
EP-1141034-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP Chemicals Limited (GB) 2001-10-10 EP disclosed
WO-2000020462-A2 BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS BP CHEMICALS LIMITED (GB) 2000-04-13 WO disclosed