SCHEMBL4603520

SCHEMBL4603520

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr]

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
CHRNB2 P17787 1/20 0.34
CHRNA4 P43681 1/20 0.34
BRD4 O60885 1/20 0.33
CYP2A6 P11509 2/20 0.32
CYP2B6 P20813 1/20 0.32
ALDH1A1 P00352 4/20 0.31
HSD17B10 Q99714 2/20 0.31
MAPK1 P28482 2/20 0.31
HPGD P15428 1/20 0.31
BCL2L1 Q07817 1/20 0.31
EDNRB P24530 1/20 0.31
EDNRA P25101 1/20 0.31
USP30 Q70CQ3 1/20 0.31
TDP1 Q9NUW8 2/20 0.31
ADRA2A P08913 2/20 0.31
ADRA2B P18089 2/20 0.31
ADRA2C P18825 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5695379 0.98 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
Hydrochloric Acid SCHEMBL28723777 0.98 PDCD1 (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
Chloromethane SCHEMBL5722647 0.97 PDCD1 (0.34) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL27474790 0.95 ADRA2A (0.35) PDCD1CD274CHRNB2CHRNA4BRD4
SCHEMBL7255779 0.91 PDCD1 (0.34) PDCD1CD274CHRNB2CHRNA4ALDH1A1
SCHEMBL27485116 0.90 EDNRB (0.34) ALDH1A1EDNRBEDNRALMNA
SCHEMBL8469895 0.89 MAOB (0.38) ALDH1A1MAPK1LMNA
SCHEMBL8469896 0.89 MAOB (0.38) ALDH1A1MAPK1LMNA
Hydrochloric Acid SCHEMBL7601938 0.88 EDNRB (0.33) ALDH1A1EDNRBEDNRATDP1LMNA
Dipyridyl SCHEMBL8678653 0.87 LMNA (0.37) PDCD1CD274CHRNB2CHRNA4CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 183 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102656198-B Process for the preparation of a particulate bimodal polyethylene product TOTAL PETROCHEMICALS RES FELUY 2014-05-28 CN claimed
CN-101827866-B Multi-component catalyst system and polymerization process for in situ formation of heterophasic copolymers and/or modification of xylene solubles content of polyolefins FINA TECHNOLOGY 2013-03-06 CN claimed
CN-102656198-A Process for the preparation of a particulate bimodal polyethylene product TOTAL PETROCHEMICALS RES FELUY 2012-09-05 CN claimed
CN-101124252-B Metallocene catalysts, their synthesis and use in olefin polymerization NOVOLEN TECH HOLDINGS CV 2011-10-05 CN claimed
CN-101883633-A Catalyst system of fluoridizing and forming method thereof FINA TECHNOLOGY 2010-11-10 CN claimed
CN-101827866-A Multi-component catalyst system and polymerization process for in situ formation of heterophasic copolymers and/or modification of xylene solubles content of polyolefins FINA TECHNOLOGY 2010-09-08 CN claimed
CN-101124252-A Metallocene catalysts, their synthesis and use in olefin polymerization NOVOLEN TECH HOLDINGS CV (NL) 2008-02-13 CN claimed
US-6583227-B2 Crystalline homo/copolymers prepared using sequential or parallel metallocene dual catalyst system; broad, bimodal molecular weight distribution; biaxially oriented and non-oriented films; even stretch at low temperature EXXONMOBIL CHEMICAL PATENTS INC. 2003-06-24 US claimed
EP-1257587-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2002-11-20 EP claimed
CN-1314918-A High activity supported catalyst composition EXXON CHEMICAL PATENTS INC (US) 2001-09-26 CN claimed
WO-2001004164-A2 HYDROGENATION OF UNSATURATED POLYMERS USING DIVALENT DIENE-CONTAINING BIS-CYCLOPENTADIENYL GROUP IV METAL CATALYSTS THE DOW CHEMICAL COMPANY (US) 2001-01-18 WO claimed
EP-1040134-A1 MIXED CATALYST SYSTEM UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-10-04 EP claimed
WO-1999031147-A1 MIXED CATALYST SYSTEM UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-06-24 WO claimed
CN-110546171-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2023-02-28 CN disclosed
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-110603274-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-09-30 CN disclosed
CN-1171097-A Norbornene compound having chain polyene group and unsaturated ethylene copolymer prepared using the same MITSUI PETROCHEMICAL IND (JP) 1998-01-21 CN disclosed
WO-1997049738-A1 INCORPORATION OF FUNCTIONALIZED COMONOMERS IN POLYOLEFINS THE DOW CHEMICAL COMPANY (US) 1997-12-31 WO disclosed
CN-1116852-A Propylene elastomer MITSUI PETROCHEMICAL IND (JP) 1996-02-14 CN disclosed
CN-1107854-A Metalocenes compound HOECHST AG (DE) 1995-09-06 CN disclosed