Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8361615 | 0.91 | MAPK1 (0.56) | CRHBPCRHR2MAPK1RAB9AGAA | |
| SCHEMBL7260691 | 0.88 | KMT2A (0.64) | MAPK1MEN1KMT2ARAB9AACACB | |
| SCHEMBL21340438 | 0.84 | MAPK1 (0.56) | MAPK1MEN1KMT2ARAB9AGAA | |
| SCHEMBL28048524 | 0.83 | MAPK1 (0.64) | MAPK1MEN1KMT2ARAB9AACACB | |
| SCHEMBL866939 | 0.82 | NPC1 (0.60) | MAPK1MEN1KMT2ARAB9AGAA | |
| SCHEMBL7256001 | 0.81 | GPR132 (0.61) | MAPK1MEN1KMT2ARAB9AACACB | |
| SCHEMBL6743382 | 0.81 | NAMPT (0.61) | CRHBPCRHR2MEN1KMT2AGAA | |
| SCHEMBL22874652 | 0.80 | MAPK1 (0.52) | MAPK1MEN1KMT2ARAB9AGAA | |
| SCHEMBL22967693 | 0.80 | MAPK1 (0.52) | MAPK1MEN1KMT2ARAB9AGAA | |
| SCHEMBL21628242 | 0.80 | KDM4E (0.65) | MAPK1MEN1KMT2ARAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003033467-A1 | NITROSO DIPHENYLAMINE DERIVATIVES AS NITROGEN MONOXIDE GENERATING AGENTS | MERCK PATENT GMBH (DE) | 2003-04-24 | — | — | WO | disclosed |