Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.51 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256139 | 1.00 | ALDH1A1 (0.51) | ALDH1A1AOX1TUBB1TDP1TRIM24 | |
| SCHEMBL7259925 | 1.00 | ALDH1A1 (0.51) | ALDH1A1AOX1TUBB1TDP1TRIM24 | |
| SCHEMBL7906957 | 0.84 | CYP2C9 (0.52) | ALDH1A1HPGDTTRRAB9ANPC1 | |
| SCHEMBL4288561 | 0.83 | ALDH1A1 (0.60) | ALDH1A1AOX1TUBB1TDP1TRIM24 | |
| SCHEMBL7258845 | 0.82 | FDPS (0.43) | ALDH1A1HPGDTTRRAB9ANPC1 | |
| SCHEMBL7259910 | 0.82 | FDPS (0.43) | ALDH1A1HPGDTTRRAB9ANPC1 | |
| SCHEMBL7255415 | 0.82 | FDPS (0.43) | ALDH1A1HPGDTTRRAB9ANPC1 | |
| SCHEMBL7258824 | 0.82 | FDPS (0.43) | ALDH1A1HPGDTTRRAB9ANPC1 | |
| SCHEMBL5220602 | 0.81 | TACR2 (0.52) | ALDH1A1HPGDRAB9ANPC1KDM4E | |
| SCHEMBL5220608 | 0.81 | TACR2 (0.52) | ALDH1A1HPGDRAB9ANPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070239-A1 | BENZYLIDENE THIAZOLIDINEDIONES AND THEIR USE AS ANTIMYCOTIC AGENTS | OXFORD GLYCOSCIENCES (UK) LTD (GB) | 2003-08-28 | — | — | WO | disclosed |