Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 7/20 | 0.41 |
| ▸ | CPB1 | P15086 | 8/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256257 | 0.87 | NAMPT (0.43) | CPB2CPB1NAMPTCPA1GRIN2B | |
| SCHEMBL5465881 | 0.81 | CPB1 (0.47) | CPB2CPB1NAMPTCPA1GRIN2B | |
| SCHEMBL5150256 | 0.79 | NAMPT (0.46) | CPB2NAMPTCPA1GRIN2BHDAC1 | |
| SCHEMBL5166294 | 0.78 | NAMPT (0.40) | CPB2NAMPTGRIN2BHDAC1GSK3B | |
| SCHEMBL7257280 | 0.77 | NAMPT (0.46) | NAMPTGRIN2BHDAC1GSK3BDYRK1A | |
| SCHEMBL7260251 | 0.76 | CPB1 (0.51) | CPB2CPB1NAMPTCPA1 | |
| SCHEMBL7260124 | 0.75 | NAMPT (0.44) | CPB2NAMPTGRIN2BHDAC1GSK3B | |
| SCHEMBL7257206 | 0.75 | CPB1 (0.46) | CPB2CPB1CPA1GRIN2B | |
| SCHEMBL12610053 | 0.74 | CPB1 (0.52) | CPB2CPB1NAMPTCPA1GRIN2B | |
| SCHEMBL31407652 | 0.74 | KLK5 (0.48) | NAMPTGRIN2BHDAC1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003013526-A1 | ANTICOAGULANT COMPOUNDS | MERCK & CO. INC. (US) | 2003-02-20 | — | — | WO | disclosed |