Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 4/20 | 0.42 |
| ▸ | JAK1 | P23458 | 3/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7261242 | 0.97 | NPC1 (0.48) | LRRK2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7255642 | 0.89 | TRPV1 (0.49) | NPC1RAB9AMAOBJAK2JAK1 | |
| SCHEMBL7261239 | 0.76 | NPC1 (0.52) | LRRK2NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7256479 | 0.75 | LRRK2 (0.53) | LRRK2NPC1RAB9AMAOBJAK2 | |
| SCHEMBL7255631 | 0.75 | RAB9A (0.55) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7259294 | 0.75 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7257003 | 0.72 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL7261208 | 0.72 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2HPGDMAOB | |
| SCHEMBL2928696 | 0.71 | NPC1 (0.51) | LRRK2NPC1RAB9AMAOBLMNA | |
| SCHEMBL16888856 | 0.70 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2HPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002518-A1 | NOVEL 2,4-DIFLUOROBENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS | DONG HWA PHARM. IND. CO., LTD. (KR) | 2003-01-09 | — | — | WO | claimed |