Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 7/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5907351 | 0.94 | F10 (0.44) | F10CD274F2 | |
| SCHEMBL5739300 | 0.89 | KDM4E (0.45) | SSTR5CD274KDM4ELMNAMEN1 | |
| SCHEMBL7256624 | 0.87 | KDM4E (0.44) | SSTR5F10KDM4ELMNAKMT2A | |
| SCHEMBL5739302 | 0.86 | SSTR5 (0.43) | SSTR5F10KDM4ELMNAKMT2A | |
| SCHEMBL5227102 | 0.86 | LMNA (0.44) | SSTR5KDM4ELMNAMEN1KMT2A | |
| SCHEMBL7256580 | 0.85 | SSTR5 (0.42) | SSTR5KDM4ELMNADRD2DRD4 | |
| SCHEMBL7257441 | 0.85 | SSTR5 (0.42) | SSTR5DRD2DRD4DRD3SMO | |
| SCHEMBL7262116 | 0.85 | SMO (0.45) | SSTR5KDM4EKMT2ADRD2DRD4 | |
| SCHEMBL1689504 | 0.85 | SMO (0.45) | SSTR5DRD2DRD4DRD3SMO | |
| SCHEMBL7260439 | 0.84 | SSTR5 (0.46) | SSTR5KDM4EDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003031435-A1 | PYRAZOLE DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS | MERCK PATENT GMBH (DE) | 2003-04-17 | — | — | WO | disclosed |