Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | SMO | Q99835 | 3/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PTAFR | P25105 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5731419 | 0.94 | SSTR5 (0.39) | SSTR5POLBSMODRD2DRD4 | |
| SCHEMBL5227102 | 0.88 | LMNA (0.44) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL1689504 | 0.87 | SMO (0.45) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7262116 | 0.87 | SMO (0.45) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL5732275 | 0.86 | SSTR5 (0.45) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7256641 | 0.85 | SSTR5 (0.40) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL5907390 | 0.85 | SSTR5 (0.42) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7256608 | 0.85 | SSTR5 (0.42) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7256580 | 0.85 | SSTR5 (0.42) | SSTR5SMODRD2DRD4DRD3 | |
| SCHEMBL7260439 | 0.84 | SSTR5 (0.46) | SSTR5SMODRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003031435-A1 | PYRAZOLE DERIVATIVES AS GLYCINE TRANSPORTER INHIBITORS | MERCK PATENT GMBH (DE) | 2003-04-17 | — | — | WO | disclosed |