Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 11/20 | 0.50 |
| ▸ | CA1 | P00915 | 10/20 | 0.50 |
| ▸ | CA2 | P00918 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 9/20 | 0.50 |
| ▸ | CA4 | P22748 | 6/20 | 0.50 |
| ▸ | CA5A | P35218 | 6/20 | 0.50 |
| ▸ | CA7 | P43166 | 6/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.50 |
| ▸ | CA6 | P23280 | 4/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7256862 | 1.00 | TSHR (0.66) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL7260809 | 1.00 | TSHR (0.66) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL9007978 | 0.83 | TSHR (0.69) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL9007982 | 0.83 | TSHR (0.69) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL4807215 | 0.82 | TSHR (0.55) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL4803932 | 0.81 | TSHR (0.53) | TSHRPTPN1CA12CA1CA2 | |
| SCHEMBL20635289 | 0.81 | TSHR (0.56) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL8945980 | 0.81 | TSHR (0.56) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL2338993 | 0.81 | TSHR (0.56) | TSHRCA12CA1CA2CA9 | |
| SCHEMBL12762931 | 0.80 | TSHR (1.00) | TSHRPTPN1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003055887-A1 | CONJUGATED PORPHYRIN, CHLORIN OR BACTERIOCHLORIN CHROMOPHORE | WELLCOME TRUST LIMITED (GB) | 2003-07-10 | — | — | WO | disclosed |