Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.51 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20635289 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNAPOLBCYP2D6 | |
| SCHEMBL2338993 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNAPOLBCYP2D6 | |
| SCHEMBL16873792 | 0.89 | TSHR (0.54) | TSHRALDH1A1CYP2D6THRBHSD17B10 | |
| SCHEMBL16873794 | 0.89 | TSHR (0.54) | TSHRALDH1A1CYP2D6THRBHSD17B10 | |
| SCHEMBL16873790 | 0.89 | TSHR (0.54) | TSHRALDH1A1CYP2D6THRBHSD17B10 | |
| SCHEMBL20635286 | 0.88 | TSHR (0.57) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL9195422 | 0.87 | TSHR (0.52) | TSHRALDH1A1LMNAPOLBCYP2D6 | |
| SCHEMBL31131003 | 0.87 | LMNA (0.48) | ALDH1A1LMNAPOLBCYP2D6THRB | |
| SCHEMBL31130942 | 0.85 | LMNA (0.48) | ALDH1A1LMNAPOLBCYP2D6THRB | |
| SCHEMBL20633976 | 0.85 | P4HB (0.61) | TSHRLMNACYP2D6THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511917-B1 | Glycosylated prodrugs, process for their preparation and uses thereof | HOECHST SA LAB (FR) | 1996-10-23 | — | — | EP | claimed |
| US-5561119-A | ANTITUMOR AGENTS | LABORATOIRES HOECHST (FR) | 1996-10-01 | — | — | US | claimed |
| US-20150192589-A1 | METHOD USING FLUORESCENT TURN-ON PROBES FOR CELL-SPECIFIC DETECTION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-07-09 | — | — | US | disclosed |
| US-20150192589-A1 | METHOD USING FLUORESCENT TURN-ON PROBES FOR CELL-SPECIFIC DETECTION | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2015-07-09 | — | — | US | disclosed |
| US-5561119-A | ANTITUMOR AGENTS | LABORATOIRES HOECHST (FR) | 1996-10-01 | — | — | US | disclosed |