Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | PDIA4 | P13667 | 1/20 | 0.51 |
| ▸ | PDIA3 | P30101 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA4 | P22748 | 3/20 | 0.50 |
| ▸ | CA6 | P23280 | 3/20 | 0.50 |
| ▸ | CA5A | P35218 | 3/20 | 0.50 |
| ▸ | CA7 | P43166 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2338993 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNAPOLBCYP2D6 | |
| SCHEMBL8945980 | 1.00 | TSHR (0.56) | TSHRALDH1A1LMNAPOLBCYP2D6 | |
| SCHEMBL16873792 | 0.89 | TSHR (0.54) | TSHRALDH1A1CYP2D6THRBHSD17B10 | |
| SCHEMBL16873794 | 0.89 | TSHR (0.54) | TSHRALDH1A1CYP2D6THRBHSD17B10 | |
| SCHEMBL16873790 | 0.89 | TSHR (0.54) | TSHRALDH1A1CYP2D6THRBHSD17B10 | |
| SCHEMBL20635286 | 0.88 | TSHR (0.57) | TSHRCYP2D6THRBHSD17B10P4HB | |
| SCHEMBL9195422 | 0.87 | TSHR (0.52) | TSHRALDH1A1LMNAPOLBCYP2D6 | |
| SCHEMBL31131003 | 0.87 | LMNA (0.48) | ALDH1A1LMNAPOLBCYP2D6THRB | |
| SCHEMBL31130942 | 0.85 | LMNA (0.48) | ALDH1A1LMNAPOLBCYP2D6THRB | |
| SCHEMBL20633976 | 0.85 | P4HB (0.61) | TSHRLMNACYP2D6THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753431-B2 | Compounds comprising cleavable linker and uses thereof | INTOCELL, INC. (KR) | 2023-09-12 | — | — | US | disclosed |
| US-11753431-B2 | Compounds comprising cleavable linker and uses thereof | INTOCELL, INC. (KR) | 2023-09-12 | — | — | US | disclosed |
| US-20220118104-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2022-04-21 | — | — | US | disclosed |
| US-20210393795-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2021-12-23 | — | — | US | disclosed |
| US-20210388017-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KP) | 2021-12-16 | — | — | US | disclosed |
| WO-2020141459-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2020141460-A2 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2020-07-09 | — | — | WO | disclosed |
| WO-2019008441-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | INTOCELL, INC. (KR) | 2019-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220118104-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | VIP, ANTXR2, TNFRSF9 | TSHR 82/4885ALDH1A1 4822/4885LMNA 3724/4885 |
| US-20210388017-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | VIP, ANTXR2, TNFRSF9 | TSHR 82/4885ALDH1A1 4822/4885LMNA 3724/4885 |
| US-11753431-B2 | Compounds comprising cleavable linker and uses thereof | VIP, ANTXR2, TNFRSF9 | TSHR 82/4885ALDH1A1 4822/4885LMNA 3724/4885 |
| US-20210393795-A1 | COMPOUNDS COMPRISING CLEAVABLE LINKER AND USES THEREOF | ANTXR2, VIP, TNFRSF9 | TSHR 138/4885ALDH1A1 4645/4885LMNA 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.