Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | CCR8 | P51685 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7257632 | 0.90 | — | — | |
| SCHEMBL7261397 | 0.80 | MIF (0.37) | CCR1CCR5CCR8 | |
| SCHEMBL1343311 | 0.74 | P2RY6 (0.30) | — | |
| SCHEMBL7258058 | 0.73 | P2RY6 (0.35) | — | |
| SCHEMBL599433 | 0.71 | CCR1 (0.57) | CCR1CCR5CCR8CYP2A6ADRA1D | |
| SCHEMBL7259986 | 0.71 | CYP2A6 (0.35) | CYP2A6 | |
| SCHEMBL7261422 | 0.70 | P2RY6 (0.33) | — | |
| SCHEMBL20550833 | 0.66 | KDM4E (0.43) | CCR1CCR5CCR8CYP2A6ADRA1D | |
| SCHEMBL7262320 | 0.65 | HSD17B10 (0.35) | — | |
| SCHEMBL9388936 | 0.64 | NPC1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
| WO-2003055887-A1 | CONJUGATED PORPHYRIN, CHLORIN OR BACTERIOCHLORIN CHROMOPHORE | WELLCOME TRUST LIMITED (GB) | 2003-07-10 | — | — | WO | disclosed |
| EP-1294726-A2 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | Catalyst Biomedica Ltd (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000662-A1 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | CATALYST BIOMEDICA LIMITED (GB) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | CCR1 2179/4885CCR5 2202/4885CCR8 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.