Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.65 |
| ▸ | CYCS | P99999 | 3/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 4/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609764 | 0.92 | TOP1 (0.55) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL3424111 | 0.87 | TOP1 (0.81) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL180349 | 0.87 | TOP1 (0.54) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL16438041 | 0.86 | TOP1 (0.79) | TOP1CYCSENPP2TERTABCG2 | |
| Hydrochloric Acid SCHEMBL8908213 | 0.86 | TOP1 (0.79) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL31337507 | 0.86 | TOP1 (0.79) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL31463633 | 0.86 | TOP1 (0.79) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL3802533 | 0.86 | TOP1 (0.79) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL31463631 | 0.86 | TOP1 (0.79) | TOP1CYCSENPP2TERTABCG2 | |
| SCHEMBL31337498 | 0.86 | TOP1 (0.79) | TOP1CYCSENPP2TERTABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030203888-A1 | Chromophores | WELLCOME TRUST LIMITED, THE (GB) | 2003-10-30 | — | — | US | disclosed |
| EP-1294726-A2 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | Catalyst Biomedica Ltd (GB) | 2003-03-26 | — | — | EP | disclosed |
| WO-2002000662-A1 | IMPROVEMENTS IN AND RELATING TO CHROMOPHORES | CATALYST BIOMEDICA LIMITED (GB) | 2002-01-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030203888-A1 | Chromophores | HCCS, PPOX, HMBS | TOP1 1754/4885CYCS 115/4885ENPP2 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.