Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | BRD4 | O60885 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2116301 | 0.77 | MEN1 (0.44) | MEN1RAB9AKMT2ABRD4ALDH1A1 | |
| SCHEMBL15148291 | 0.76 | BRD4 (0.50) | MEN1RAB9AKMT2ABRD4ALDH1A1 | |
| SCHEMBL27295583 | 0.74 | ACLY (0.43) | MEN1RAB9AKMT2ABRD4ALDH1A1 | |
| SCHEMBL14993737 | 0.74 | AURKA (0.49) | MEN1RAB9AKMT2ABRD4ALDH1A1 | |
| SCHEMBL19513805 | 0.74 | MEN1 (0.41) | MEN1RAB9AKMT2ABRD4ALDH1A1 | |
| SCHEMBL1983704 | 0.74 | MEN1 (0.41) | MEN1RAB9AKMT2ABRD4ALDH1A1 | |
| SCHEMBL16651268 | 0.74 | BRD4 (0.39) | BRD4DAOTYR | |
| SCHEMBL20385259 | 0.74 | TYR (0.39) | BRD4DAOTYRBRD9 | |
| SCHEMBL2975718 | 0.74 | KMT2A (0.60) | MEN1RAB9AKMT2ABRD4ALDH1A1 | |
| SCHEMBL21026434 | 0.74 | MEN1 (0.45) | MEN1RAB9AKMT2ABRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103668-A1 | PYRIDIN-2-ONE AND QUINOLIN-2-ONE DERIVATIVES, PREPARATION THEREOF AND USE THEREOF AS ANTIBACTERIALS | KARO BIO AB (SE) | 2003-12-18 | — | — | WO | disclosed |