Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | BRD4 | O60885 | 8/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | TTK | P33981 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22516630 | 0.76 | BRD4 (0.50) | BRD4BRD9 | |
| SCHEMBL13456010 | 0.74 | AURKA (0.49) | BRD4BRD9AURKATTKAURKB | |
| SCHEMBL16651268 | 0.74 | BRD4 (0.39) | TYRBRD4DAOL3MBTL1 | |
| SCHEMBL7257366 | 0.74 | MEN1 (0.45) | TYRBRD4DAOBRD9 | |
| SCHEMBL18508339 | 0.72 | CREBBP (0.35) | BRD4BRD9 | |
| SCHEMBL24556428 | 0.71 | CREBBP (0.39) | BRD4L3MBTL1BRD9 | |
| SCHEMBL24556434 | 0.71 | BRD4 (0.36) | BRD4BRD9 | |
| SCHEMBL24007175 | 0.68 | QDPR (0.42) | BRD4DAOBRD9 | |
| SCHEMBL13272808 | 0.68 | GPR35 (0.43) | L3MBTL1 | |
| SCHEMBL24120268 | 0.67 | ESR1 (0.38) | TYRBRD4DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018130227-A1 | AROMATIC RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION, AND USE | 山东罗欣药业集团股份有限公司 | 2018-07-19 | — | — | WO | disclosed |