Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.50 |
| ▸ | ACE | P12821 | 5/20 | 0.50 |
| ▸ | CPA1 | P15085 | 5/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 5/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.49 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7898943 | 0.93 | NOD2 (0.49) | MMEHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL236628 | 0.88 | MME (0.55) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL29755521 | 0.85 | ACE (0.55) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL7257453 | 0.85 | MME (0.55) | MMEACECPA1ACE2HDAC3 | |
| SCHEMBL2980529 | 0.83 | NAALAD2 (0.68) | MMEACECPA1ACE2NAALAD2 | |
| SCHEMBL3748615 | 0.83 | NAALAD2 (0.68) | MMEACECPA1ACE2NAALAD2 | |
| SCHEMBL29602993 | 0.83 | NAALAD2 (0.68) | MMEACECPA1ACE2NAALAD2 | |
| SCHEMBL3732243 | 0.83 | NAALAD2 (0.68) | MMEACECPA1ACE2NAALAD2 | |
| SCHEMBL27914476 | 0.83 | NAALAD2 (0.68) | MMEACECPA1ACE2NAALAD2 | |
| SCHEMBL5971011 | 0.83 | MME (0.52) | MMEACECPA1ACE2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728018-B1 | New enzymes and prodrugs for ADEPT | WELLCOME FOUND (GB) | 2003-08-06 | — | — | EP | disclosed |