Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.54 |
| ▸ | ACLY | P53396 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TCF4 | P15884 | 2/20 | 0.52 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | LOX | P28300 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262403 | 0.87 | F2 (0.61) | ACLYKDM4EKMT2ACA1CA2 | |
| SCHEMBL10922923 | 0.87 | TSHR (0.56) | ALDH1A1KMT2ACA1CA2LMNA | |
| SCHEMBL11278869 | 0.87 | SLC40A1 (0.56) | SLC40A1ACLYPOLBTCF4CTNNB1 | |
| Hydrochloric Acid SCHEMBL11541160 | 0.86 | F2 (0.59) | ACLYKDM4EKMT2ACA1CA2 | |
| SCHEMBL10722426 | 0.86 | ALDH1A1 (0.48) | SLC40A1ACLYALDH1A1KDM4EKMT2A | |
| SCHEMBL3476507 | 0.85 | TDP1 (0.60) | SLC40A1ACLYPOLBTCF4CTNNB1 | |
| SCHEMBL2884607 | 0.83 | LOX (0.66) | SLC40A1ACLYPOLBTCF4CTNNB1 | |
| SCHEMBL15625460 | 0.83 | SLC40A1 (0.53) | SLC40A1ACLYPOLBTCF4CTNNB1 | |
| SCHEMBL28667831 | 0.83 | POLB (0.51) | SLC40A1ACLYPOLBTCF4CTNNB1 | |
| SCHEMBL7636575 | 0.82 | SLC40A1 (0.50) | SLC40A1ACLYPOLBTCF4CTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693438-A | Synthesis process of sulpride | 焦作福瑞堂制药有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-112441960-B | Synthetic method of sulpiride | 常州康普药业有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-112441960-A | Synthetic method of sulpiride | 常州康普药业有限公司 | 2021-03-05 | — | — | CN | claimed |
| CN-118496140-A | Refining method of sulpiride | 杭州国瑞生物科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| CN-116693438-A | Synthesis process of sulpride | 焦作福瑞堂制药有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116693438-A | Synthesis process of sulpride | 焦作福瑞堂制药有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-112441960-B | Synthetic method of sulpiride | 常州康普药业有限公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-112441960-A | Synthetic method of sulpiride | 常州康普药业有限公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-108660131-B | Preparation method of immobilized nitrile hydratase and (S) -N-ethylpyrrolidine-2-formamide | 浙江工业大学 | 2020-07-21 | — | — | CN | disclosed |
| CN-105646295-A | Method for preparing 2-methoxy-5-sulfamoyl methyl benzoate | 苏州诚和医药化学有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105646294-A | Method for synthesizing 2-methoxy-5-sulfamoylmethyl benzoate | 苏州诚和医药化学有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105646295-A | Method for preparing 2-methoxy-5-sulfamoyl methyl benzoate | 苏州诚和医药化学有限公司 | 2016-06-08 | — | — | CN | disclosed |
| CN-105503666-A | Method for conveniently synthesizing 2-methoxy-5-sulfamoyl methyl benzoate | SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-105503666-A | Method for conveniently synthesizing 2-methoxy-5-sulfamoyl methyl benzoate | SUZHOU CHENGHE PHARMACEUTICAL & CHEMICAL CO LTD | 2016-04-20 | — | — | CN | disclosed |
| CN-1884259-A | Process for preparing 2-methoxyl-5-amino sulfonyl methyl benzoate | UNIV NANKAI (CN) | 2006-12-27 | — | — | CN | disclosed |
| WO-2003055857-A1 | A PROCESS FOR SYNTHESIS OF HETEROCYCLIC AMINOALKYL BENZAMIDES | FARMACEUTSKO-HEMIJSKA INDUSTRIJA 'ZDRAVLJE' (YU) | 2003-07-10 | — | — | WO | disclosed |
| US-4673686-A | CNS MODIFIERS, ANTI-APOMORPHINE ANTIENETIC ACITIVTY/ | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLE DE L'ILE DE FRANCE (FR) | 1987-06-16 | — | — | US | disclosed |