Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 16/20 | 0.41 |
| ▸ | DRD3 | P35462 | 16/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252658 | 0.86 | DRD2 (0.50) | DRD2DRD3 | |
| SCHEMBL4392640 | 0.85 | DRD2 (0.53) | DRD2DRD3HRH3 | |
| SCHEMBL5899239 | 0.84 | DRD2 (0.59) | DRD2DRD3 | |
| SCHEMBL4392037 | 0.83 | DRD2 (0.49) | DRD2DRD3 | |
| SCHEMBL7255646 | 0.83 | DRD2 (0.42) | DRD2DRD3HRH3 | |
| SCHEMBL388042 | 0.81 | DRD2 (0.45) | DRD2DRD3 | |
| SCHEMBL2354731 | 0.79 | DRD2 (0.60) | DRD2DRD3 | |
| SCHEMBL1998919 | 0.75 | DRD2 (0.73) | DRD2DRD3 | |
| SCHEMBL4392571 | 0.75 | DRD2 (0.54) | DRD2DRD3 | |
| SCHEMBL1999004 | 0.74 | DRD3 (0.72) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003002543-A1 | PYRIMIDINOXYALKYLPIPERAZINES AND THEIR THERAPEUTIC USE | ABBOTT LABORATORIES (US) | 2003-01-09 | — | — | WO | disclosed |