Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.69 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.56 |
| ▸ | ITGAL | P20701 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CPB1 | P15086 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4653523 | 0.99 | SLC6A5 (0.69) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| SCHEMBL7887542 | 0.99 | SLC6A5 (0.69) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| SCHEMBL541262 | 0.96 | SLC15A2 (0.67) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| SCHEMBL26126281 | 0.96 | SLC15A2 (0.67) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| SCHEMBL21631681 | 0.96 | SLC15A2 (0.67) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| Carnosine SCHEMBL22191128 | 0.95 | SLC15A2 (0.69) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| Carnosine SCHEMBL22392772 | 0.91 | SLC15A2 (0.63) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| Carnosine SCHEMBL1161102 | 0.91 | SLC15A2 (0.63) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| Carnosine SCHEMBL1160796 | 0.91 | SLC15A2 (0.63) | SLC15A2SLC6A5EPHX2CPB2ITGB2 | |
| SCHEMBL19059414 | 0.90 | SLC6A5 (0.70) | SLC15A2SLC6A5EPHX2CPB2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972511-B1 | Association of a retinoid with a histidine derivative | OREAL (FR) | 2003-04-09 | — | — | EP | disclosed |
| US-6358514-B1 | FOR SKIN AND HAIRCARE | L'OREAL (FR) | 2002-03-19 | — | — | US | disclosed |
| EP-0972511-A1 | Association of a retinoid with a histidine derivative | L'OREAL (FR) | 2000-01-19 | — | — | EP | disclosed |
| EP-0962453-A1 | Histidine derivatives, process for their preparation and their uses | L'OREAL (FR) | 1999-12-08 | — | — | EP | disclosed |
| WO-1999047504-A1 | NOVEL HISTIDINE DERIVATIVES PREPARATION METHOD AND USES | L'OREAL (FR) | 1999-09-23 | — | — | WO | disclosed |