Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.69 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.56 |
| ▸ | ITGB2 | P05107 | 3/20 | 0.55 |
| ▸ | ICAM1 | P05362 | 3/20 | 0.55 |
| ▸ | ITGAL | P20701 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7887542 | 1.00 | SLC6A5 (0.69) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| SCHEMBL7257727 | 0.99 | SLC15A2 (0.69) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| SCHEMBL26126281 | 0.95 | SLC15A2 (0.67) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| SCHEMBL541262 | 0.95 | SLC15A2 (0.67) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| SCHEMBL21631681 | 0.95 | SLC15A2 (0.67) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| Carnosine SCHEMBL22191128 | 0.94 | SLC15A2 (0.69) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| SCHEMBL18857761 | 0.90 | SLC15A2 (0.58) | SLC6A5SLC15A2EPHX2CPB2HRH4 | |
| Carnosine SCHEMBL22392772 | 0.90 | SLC15A2 (0.63) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| Carnosine SCHEMBL1160796 | 0.90 | SLC15A2 (0.63) | SLC6A5SLC15A2EPHX2CPB2ITGB2 | |
| Carnosine SCHEMBL1161102 | 0.90 | SLC15A2 (0.63) | SLC6A5SLC15A2EPHX2CPB2ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972511-B1 | Association of a retinoid with a histidine derivative | OREAL (FR) | 2003-04-09 | — | — | EP | claimed |
| US-6358514-B1 | FOR SKIN AND HAIRCARE | L'OREAL (FR) | 2002-03-19 | — | — | US | claimed |
| EP-0972511-A1 | Association of a retinoid with a histidine derivative | L'OREAL (FR) | 2000-01-19 | — | — | EP | claimed |
| WO-1999047504-A1 | NOVEL HISTIDINE DERIVATIVES PREPARATION METHOD AND USES | L'OREAL (FR) | 1999-09-23 | — | — | WO | claimed |
| EP-1602354-B1 | Use of polyglutamic acid or its salts | MEIJI SEIKA KAISHA (JP) | 2008-11-05 | — | — | EP | disclosed |
| EP-1604647-B1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | CHISSO CORP (JP) | 2008-05-07 | — | — | EP | disclosed |
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | MEIJI SEIKA KAISHA, LTD. (JP) | 2006-07-27 | — | — | US | disclosed |
| US-20060018867-A1 | Cosmetic composition and production thereof | ICHIMARU PHARCOS CO., LTD | 2006-01-26 | — | — | US | disclosed |
| EP-1604647-A1 | Cosmetic composition containing polyorganosiloxane-containing epsilon-polylysine polymer, and polyhydric alcohol, and production thereof | Ichimaru Pharcos Co., Ltd. (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1602354-A1 | HAIR TREATMENT COMPOSITION AND HAIR COSMETIC FOR DAMAGED HAIR | Meiji Seika Kaisha, Ltd. (JP) | 2005-12-07 | — | — | EP | disclosed |
| EP-0972511-B1 | Association of a retinoid with a histidine derivative | OREAL (FR) | 2003-04-09 | — | — | EP | disclosed |
| US-6358514-B1 | FOR SKIN AND HAIRCARE | L'OREAL (FR) | 2002-03-19 | — | — | US | disclosed |
| EP-0972511-A1 | Association of a retinoid with a histidine derivative | L'OREAL (FR) | 2000-01-19 | — | — | EP | disclosed |
| WO-1999047504-A1 | NOVEL HISTIDINE DERIVATIVES PREPARATION METHOD AND USES | L'OREAL (FR) | 1999-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165636-A1 | Hair treatment composition and hair cosmetic for damaged hair | CUTA, COL14A1, PRKDC | SLC6A5 1664/4885SLC15A2 819/4885EPHX2 4734/4885 |
| US-20060018867-A1 | Cosmetic composition and production thereof | CUTA, PARG, TYR | SLC6A5 3000/4885SLC15A2 4199/4885EPHX2 2379/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.