Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 11/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196308 | 0.87 | ACHE (0.51) | CHRM2CHRM1CHRM3OPRM1CHRM4 | |
| SCHEMBL7167171 | 0.86 | ALDH1A1 (0.48) | CHRM2CHRM1CHRM3OPRM1CHRM4 | |
| SCHEMBL7257638 | 0.86 | CHRM3 (0.44) | CHRM2CHRM1CHRM3OPRM1CHRM4 | |
| SCHEMBL7190540 | 0.85 | CHRM3 (0.46) | CHRM2CHRM1CHRM3OPRM1CHRM4 | |
| SCHEMBL7251853 | 0.84 | CHRM3 (0.45) | CHRM2CHRM1CHRM3OPRM1CHRM4 | |
| SCHEMBL7139282 | 0.84 | ACHE (0.49) | CHRM2CHRM3OPRM1CHRM4BCHE | |
| SCHEMBL7257336 | 0.83 | CHRM3 (0.44) | CHRM2CHRM1CHRM3OPRM1CHRM4 | |
| SCHEMBL7149576 | 0.80 | BCHE (0.54) | CHRM2CHRM1CHRM4BCHEACHE | |
| SCHEMBL7256616 | 0.77 | CYP3A4 (0.50) | CHRM2CHRM3OPRM1CACNA1BACHE | |
| SCHEMBL7149783 | 0.76 | ACHE (0.54) | CHRM2CHRM3OPRM1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030176461-A1 | Aminopiperidines | NPS ALLELIX CORP. (CANADA CORPORATION) (CA) | 2003-09-18 | — | — | US | claimed |
| US-20030176461-A1 | Aminopiperidines | NPS ALLELIX CORP. (CANADA CORPORATION) (CA) | 2003-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176461-A1 | Aminopiperidines | SLC1A2, SLC6A4, SLC1A1 | CHRM2 320/4885CHRM1 197/4885CHRM3 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.