Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | DKK1 | O94907 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 9/20 | 0.40 |
| ▸ | PTPRF | P10586 | 2/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10973666 | 0.80 | GSK3B (0.55) | GSK3BDKK1CDK2DYRK1AHSD17B10 | |
| SCHEMBL10019584 | 0.75 | DYRK1A (0.48) | GSK3BDKK1CDK2DYRK1AHSD17B10 | |
| SCHEMBL10019585 | 0.73 | DYRK1A (0.49) | GSK3BDKK1CDK2DYRK1AHSD17B10 | |
| SCHEMBL10973799 | 0.73 | GSK3B (0.51) | GSK3BDKK1CDK2DYRK1A | |
| SCHEMBL27139968 | 0.70 | DYRK1A (0.49) | GSK3BDKK1CDK2DYRK1AJAK2 | |
| SCHEMBL27154223 | 0.70 | DYRK1A (0.48) | GSK3BDKK1CDK2DYRK1AJAK2 | |
| SCHEMBL28886710 | 0.69 | AURKA (0.55) | DYRK1AJAK3 | |
| SCHEMBL10972910 | 0.69 | NPC1 (0.51) | GSK3BKDRCDK2DYRK1A | |
| SCHEMBL7263622 | 0.68 | UQCRB (0.58) | PTPRBPTPN2PTPN1PTPN11 | |
| SCHEMBL5914145 | 0.68 | IKBKB (0.37) | GSK3BDKK1IKBKBCDK2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |