Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER2 | P43116 | 9/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263344 | 0.96 | PTGER2 (0.35) | PTGER2LMNAMAPTKMT2AESR1 | |
| SCHEMBL5855191 | 0.94 | PTGER2 (0.33) | PTGER2LMNAMAPTKMT2AESR1 | |
| SCHEMBL5855042 | 0.90 | CYP19A1 (0.33) | PTGER2PTGER4PTGER3PPARAHTT | |
| SCHEMBL5854085 | 0.86 | PTGER2 (0.33) | PTGER2PTGER4PTGER3HTTHSD17B3 | |
| SCHEMBL7257977 | 0.84 | ALOX5 (0.34) | — | |
| SCHEMBL5854635 | 0.79 | TBXA2R (0.35) | PTGER2LMNAMAPTKMT2AESR1 | |
| SCHEMBL7262813 | 0.79 | TBXA2R (0.35) | PTGER2LMNAMAPTKMT2AESR1 | |
| SCHEMBL7258633 | 0.79 | TBXA2R (0.35) | PTGER2LMNAMAPTKMT2AESR1 | |
| SCHEMBL5856053 | 0.79 | HSD17B3 (0.33) | HSD17B3 | |
| SCHEMBL5854558 | 0.77 | OPRM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645951-B1 | Antiestrogens for treating breast cancer | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2003-11-11 | — | — | US | disclosed |