Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.32 |
| ▸ | MERTK | Q12866 | 1/20 | 0.32 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.32 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879783 | 0.83 | PTPN11 (0.37) | PTPN11DNM1GPR84ARFLT3 | |
| SCHEMBL15877149 | 0.83 | GBA1 (0.39) | DNM1RAB9AGBA1NPC1NFKB1 | |
| SCHEMBL17967543 | 0.81 | DNM1 (0.40) | DNM1RAB9AGBA1NPC1NFKB1 | |
| SCHEMBL17967579 | 0.81 | DNM1 (0.40) | DNM1RAB9AGBA1NPC1NFKB1 | |
| SCHEMBL17654205 | 0.78 | GBA1 (0.44) | RAB9AGBA1NPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7254985 | 0.77 | GBA1 (0.40) | RAB9AGBA1NPC1NFKB1MAPK1 | |
| SCHEMBL13271174 | 0.75 | GBA1 (0.33) | GBA1 | |
| SCHEMBL3606370 | 0.74 | ACACB (0.41) | MAPK1EHMT2EHMT1 | |
| SCHEMBL12889037 | 0.74 | PTPN11 (0.40) | PTPN11ARFLT3TYRO3MERTK | |
| SCHEMBL31217157 | 0.71 | GBA1 (0.56) | PTPN11RAB9AGBA1ARNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003040132-A1 | Δ1-PYRROLINES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | WO | disclosed |
| WO-2003040092-A2 | $g(D)1-PYRROLINES | BAYER AKTIENGESELLSCHAFT (DE) | 2003-05-15 | — | — | WO | disclosed |