Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | AR | P10275 | 2/20 | 0.48 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | CCNC | P24863 | 3/20 | 0.40 |
| ▸ | CDK8 | P49336 | 3/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 3/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8366506 | 0.85 | PRKDC (0.51) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28383699 | 0.79 | CYP1A2 (0.52) | RAB9ASMN1; SMN2KDM4EALDH1A1AR | |
| SCHEMBL28384841 | 0.79 | ALDH1A1 (0.56) | HPGDRAB9ASMN1; SMN2ALDH1A1AR | |
| SCHEMBL28384631 | 0.79 | ALDH1A1 (0.56) | HPGDRAB9ASMN1; SMN2ALDH1A1AR | |
| SCHEMBL28383892 | 0.79 | CYP1A2 (0.52) | RAB9ASMN1; SMN2KDM4EALDH1A1AR | |
| SCHEMBL6827288 | 0.79 | TNKS (0.51) | ARPRKDCCCNCCDK8PLA2G2A | |
| SCHEMBL6827690 | 0.79 | TNKS (0.51) | ARPRKDCCCNCCDK8PLA2G2A | |
| SCHEMBL6824581 | 0.78 | EGFR (0.58) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL28887784 | 0.78 | EGFR (0.58) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL7258144 | 0.77 | ALDH1A1 (0.58) | HPGDRAB9ASMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006451-A1 | 4-PHENYLPYRAN-2-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2003-01-23 | — | — | WO | disclosed |