Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258141 | 0.77 | HPGD (0.55) | ALDH1A1ARKDM4EGLAGAA | |
| SCHEMBL3415966 | 0.74 | ALDH1A1 (0.67) | ALDH1A1TSHRARKDM4EMAPT | |
| SCHEMBL10528160 | 0.71 | ALDH1A1 (0.50) | ALDH1A1PTGS2HAO1PTGS1 | |
| SCHEMBL10300271 | 0.71 | ALDH1A1 (0.50) | ALDH1A1PTGS2HAO1PTGS1 | |
| SCHEMBL18876468 | 0.69 | TAAR1 (0.55) | ALDH1A1TSHRARKDM4EGLA | |
| SCHEMBL7030833 | 0.68 | CA1 (0.44) | ALDH1A1ARKDM4EGLAGAA | |
| SCHEMBL11779535 | 0.68 | ALDH1A1 (0.61) | ALDH1A1ARKDM4EGLAGAA | |
| SCHEMBL20428325 | 0.67 | HPGD (0.61) | ALDH1A1ARKDM4EGLAGAA | |
| SCHEMBL17283465 | 0.67 | PTGS2 (0.63) | ALDH1A1GAARAB9APTGS2HAO1 | |
| SCHEMBL403028 | 0.67 | PTGS2 (0.63) | ALDH1A1GAARAB9APTGS2HAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003006451-A1 | 4-PHENYLPYRAN-2-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2003-01-23 | — | — | WO | disclosed |