SCHEMBL7785071

SCHEMBL7785071

O=C(O)c1ccc(Oc2ccc(Oc3ccccc3-c3ccccc3)cc2)cc1C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.60
NCOA1 Q15788 1/20 0.54
NCOA3 Q9Y6Q9 1/20 0.54
TDP1 Q9NUW8 2/20 0.53
GALK1 P51570 1/20 0.53
CASP6 P55212 1/20 0.53
MCL1 Q07820 1/20 0.53
PLEC Q15149 1/20 0.53
PYGL P06737 6/20 0.50
PYGM P11217 7/20 0.49
HPSE Q9Y251 1/20 0.49
FFAR4 Q5NUL3 1/20 0.49
LMNA P02545 1/20 0.45
FEN1 P39748 1/20 0.45
FFAR1 O14842 1/20 0.44
KDM4E B2RXH2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3919045 0.97 POLB (0.55) POLBNCOA1NCOA3TDP1GALK1
SCHEMBL7258190 0.92 POLB (0.65) POLBTDP1GALK1CASP6MCL1
SCHEMBL7785073 0.91 POLB (0.60) POLBTDP1GALK1CASP6MCL1
SCHEMBL28480681 0.91 GALK1 (0.53) POLBNCOA1NCOA3TDP1GALK1
SCHEMBL7257602 0.89 POLB (0.59) POLBTDP1GALK1CASP6MCL1
SCHEMBL7627578 0.86 GALK1 (0.51) POLBNCOA1NCOA3TDP1GALK1
SCHEMBL8652192 0.84 POLB (0.71) POLBTDP1GALK1CASP6MCL1
SCHEMBL6891584 0.84 POLB (0.66) POLBTDP1GALK1CASP6MCL1
SCHEMBL7969637 0.84 POLB (0.65) POLBTDP1GALK1CASP6MCL1
SCHEMBL29664286 0.84 POLB (0.65) POLBTDP1GALK1CASP6MCL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010031853-A1 Melt processable PMR-type polyimides UNIVERSITY OF AKRON, THE 2001-10-18 US claimed