Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7252993 | 0.91 | SMN1; SMN2 (0.38) | SCN9ASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7258218 | 0.85 | KMT2A (0.39) | SMN1; SMN2ALDH1A1KMT2AKDM4EMAPK1 | |
| SCHEMBL7252990 | 0.83 | KMT2A (0.39) | SCN9ASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7253101 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1KMT2AKDM4EMAPK1 | |
| SCHEMBL17962150 | 0.78 | KMT2A (0.41) | SCN9ASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL7676064 | 0.77 | PTGDR2 (0.42) | SMN1; SMN2ALDH1A1KMT2AKDM4EMAPK1 | |
| SCHEMBL7676069 | 0.77 | PTGDR2 (0.42) | SMN1; SMN2ALDH1A1KMT2AKDM4EMAPK1 | |
| SCHEMBL4064134 | 0.77 | SCN9A (0.45) | SCN9ASMN1; SMN2ALDH1A1KMT2AKDM4E | |
| SCHEMBL17962153 | 0.76 | MAPK1 (0.50) | SMN1; SMN2ALDH1A1KMT2AKDM4EMAPK1 | |
| SCHEMBL23673696 | 0.75 | MAPK1 (0.43) | SMN1; SMN2ALDH1A1KMT2AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003029226-A1 | HETEROCYCLYL SUBSTITUTED PHENOXYALKYL-, PHENYLTHIOALKYL-, PHENYLAMINOALKYL- AND PHENYLALKYL-SULFAMOYLCARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-10 | — | — | WO | disclosed |