Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066356 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2GAALMNAKMT2AALDH1A1 | |
| SCHEMBL7258222 | 0.77 | SCN9A (0.41) | SCN9ASMN1; SMN2GAALMNAKMT2A | |
| SCHEMBL31118371 | 0.77 | SCN9A (0.45) | SCN9APOLBCYP2C19 | |
| SCHEMBL7252993 | 0.76 | SMN1; SMN2 (0.38) | SCN9ASMN1; SMN2GAALMNAKMT2A | |
| SCHEMBL7258218 | 0.74 | KMT2A (0.39) | SMN1; SMN2GAALMNAKMT2AALDH1A1 | |
| SCHEMBL7252990 | 0.74 | KMT2A (0.39) | SCN9ASMN1; SMN2GAALMNAKMT2A | |
| SCHEMBL713577 | 0.74 | SCN9A (0.46) | SCN9APOLBCYP2C19 | |
| SCHEMBL25410858 | 0.72 | L3MBTL1 (0.46) | SMN1; SMN2GAALMNAKMT2AALDH1A1 | |
| SCHEMBL25413185 | 0.72 | L3MBTL1 (0.46) | SMN1; SMN2GAALMNAKMT2AALDH1A1 | |
| SCHEMBL25410861 | 0.72 | L3MBTL1 (0.46) | SMN1; SMN2GAALMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226127-B1 | SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF SE (DE) | 2009-07-01 | — | — | EP | claimed |
| US-6689773-B2 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | claimed |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CARLSEN MARIANNE (US) | 2003-12-04 | — | — | US | claimed |
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) | 2002-04-18 | — | — | US | claimed |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CARLSEN MARIANNE | 2004-11-04 | — | — | US | disclosed |
| US-6689773-B2 | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-10 | — | — | US | disclosed |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CARLSEN MARIANNE (US) | 2003-12-04 | — | — | US | disclosed |
| US-6534492-B2 | Herbicidal phenylsulfamoyl carboxamides | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-18 | — | — | US | disclosed |
| EP-1226127-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-31 | — | — | EP | disclosed |
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | INTELLECTUAL PROPERTY DEPARTMENT BASF AKTIENGESELLSCHAFT (DE) | 2002-04-18 | — | — | US | disclosed |
| WO-2001083459-A2 | URACIL SUBSTITUTED PHENYL SULFAMOYL CARBOXAMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-11-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020045550-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | SCN9A 2296/4885SMN1; SMN2 3027/4885GAA 1530/4885 |
| US-20030224941-A1 | Uracil substituted phenyl sulfamoyl carboxamides | CCNH, CBR3, UNG | SCN9A 2296/4885SMN1; SMN2 3027/4885GAA 1530/4885 |
| US-20040220172-A1 | Herbicidal compositions for the desiccation/ defoliation of plants | CBR3, HDHD5, DDAH1 | SCN9A 1794/4885SMN1; SMN2 3580/4885GAA 1407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.