Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.57 |
| ▸ | MEN1 | O00255 | 10/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492687 | 0.84 | KDM4E (0.58) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL19259536 | 0.83 | KDM4E (0.57) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL19303544 | 0.81 | TSHR (0.63) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL19997314 | 0.80 | SLC22A12 (0.58) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL28112717 | 0.77 | MAPK1 (0.56) | KDM4EKMT2AMEN1L3MBTL1MAPT | |
| SCHEMBL6087090 | 0.76 | MEN1 (0.60) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL24980451 | 0.75 | MEN1 (0.65) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL14127702 | 0.75 | KMT2A (0.55) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL29636514 | 0.75 | KMT2A (0.55) | KDM4EPOLBKMT2AMEN1PABPC1 | |
| SCHEMBL1036983 | 0.74 | MEN1 (0.69) | KDM4EPOLBKMT2AMEN1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |