Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1037705 | 0.83 | MEN1 (0.59) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL5335902 | 0.81 | MEN1 (0.57) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL1038586 | 0.79 | MEN1 (0.65) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL6087090 | 0.78 | MEN1 (0.60) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL24980040 | 0.78 | KMT2A (0.44) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL16492687 | 0.77 | KDM4E (0.58) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL24980449 | 0.76 | PIK3CB (0.59) | KMT2AHTTSMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL9413326 | 0.76 | POLB (0.56) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL7258442 | 0.75 | KDM4E (0.57) | MEN1KMT2APABPC1HTTSMN1; SMN2 | |
| SCHEMBL19259536 | 0.75 | KDM4E (0.57) | MEN1KMT2APABPC1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230032020-A1 | SMALL-MOLECULE COVALENT INHIBITION OF RAL GTPASES | NATIONAL INSTITUTES OF HEALTH | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230032020-A1 | SMALL-MOLECULE COVALENT INHIBITION OF RAL GTPASES | RALA, KRAS, HRAS | MEN1 2431/4885KMT2A 487/4885PABPC1 3508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.