Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.56 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16492687 | 0.84 | KDM4E (0.58) | KDM4EPOLBMEN1KMT2APABPC1 | |
| SCHEMBL7258442 | 0.83 | KDM4E (0.57) | KDM4EPOLBMEN1KMT2APABPC1 | |
| SCHEMBL19303544 | 0.81 | TSHR (0.63) | KDM4EPOLBMEN1KMT2APABPC1 | |
| SCHEMBL19997314 | 0.80 | SLC22A12 (0.58) | KDM4EPOLBMEN1KMT2APABPC1 | |
| SCHEMBL19259540 | 0.77 | CA1 (0.52) | CA1CA2 | |
| SCHEMBL6087090 | 0.76 | MEN1 (0.60) | KDM4EPOLBCA1CA2MEN1 | |
| SCHEMBL15556986 | 0.76 | MEN1 (0.67) | KDM4EPOLBMEN1KMT2APABPC1 | |
| SCHEMBL31252505 | 0.76 | KMT2A (0.51) | KDM4EPOLBMEN1KMT2APABPC1 | |
| SCHEMBL1491147 | 0.76 | KMT2A (0.51) | KDM4EPOLBMEN1KMT2APABPC1 | |
| SCHEMBL24980451 | 0.75 | MEN1 (0.65) | KDM4EPOLBMEN1KMT2APABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3416948-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | The University Of Queensland (AU) | 2018-12-26 | — | — | EP | disclosed |
| WO-2017140778-A1 | SULFONYLUREAS AND RELATED COMPOUNDS AND USE OF SAME | THE UNIVERSITY OF QUEENSLAND (AU) | 2017-08-24 | — | — | WO | disclosed |