Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | PKM | P14618 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1080825 | 0.82 | KMT2A (0.63) | KMT2APKMTSHRSMN1; SMN2GAA | |
| SCHEMBL19500873 | 0.81 | KMT2A (1.00) | KMT2APKMTSHRSMN1; SMN2GAA | |
| SCHEMBL19667559 | 0.77 | KMT2A (0.57) | KMT2APKMTSHRSMN1; SMN2GAA | |
| SCHEMBL15624560 | 0.74 | MPO (0.50) | KMT2APKMTSHRGAAHSD17B10 | |
| SCHEMBL7258443 | 0.73 | KMT2A (0.52) | KMT2APKMTSHRSMN1; SMN2HSD17B10 | |
| SCHEMBL6076008 | 0.73 | GRM5 (0.62) | KMT2ASMN1; SMN2GAAHSD17B10HPGD | |
| SCHEMBL29195354 | 0.72 | KMT2A (0.82) | KMT2APKMTSHRSMN1; SMN2GAA | |
| SCHEMBL6944267 | 0.72 | KMT2A (0.83) | KMT2APKMTSHRSMN1; SMN2HPGD | |
| SCHEMBL281216 | 0.72 | SCN9A (0.53) | KMT2APKMTSHRSMN1; SMN2GAA | |
| SCHEMBL31751934 | 0.71 | KMT2A (0.65) | KMT2AHPGDMEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067935-B1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1067935-A4 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1067935-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | The Regents of the University of California (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6124278-A | COGNITION ACTIVATORS FOR LEARNING/MEMORY ENHANCEMENT AND TREATMENT OF BRAIN/PSYCHOLOGICAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999051240-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-10-14 | — | — | WO | disclosed |