Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262450 | 0.94 | KMT2A (0.45) | KMT2APKMTSHRSMN1; SMN2RXFP1 | |
| SCHEMBL7263664 | 0.84 | RXFP1 (0.39) | KMT2APKMTSHRSMN1; SMN2RXFP1 | |
| SCHEMBL1080825 | 0.73 | KMT2A (0.63) | KMT2APKMTSHRSMN1; SMN2HPGD | |
| SCHEMBL7258452 | 0.73 | KMT2A (0.68) | KMT2APKMTSHRSMN1; SMN2HPGD | |
| SCHEMBL7262414 | 0.73 | ALDH1A1 (0.35) | KMT2ATSHRSMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL19500873 | 0.69 | KMT2A (1.00) | KMT2APKMTSHRSMN1; SMN2HPGD | |
| SCHEMBL7258246 | 0.66 | RAB9A (0.35) | KMT2ASMN1; SMN2HPGDMAPTALDH1A1 | |
| SCHEMBL3802555 | 0.65 | PKM (0.68) | KMT2APKMTSHRSMN1; SMN2RXFP1 | |
| SCHEMBL1856211 | 0.65 | KMT2A (0.49) | KMT2APKMTSHRSMN1; SMN2RXFP1 | |
| SCHEMBL1856209 | 0.65 | KMT2A (0.49) | KMT2APKMTSHRSMN1; SMN2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067935-B1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2003-08-20 | — | — | EP | disclosed |
| EP-1067935-A4 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | UNIV CALIFORNIA (US) | 2001-10-04 | — | — | EP | disclosed |
| EP-1067935-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | The Regents of the University of California (US) | 2001-01-17 | — | — | EP | disclosed |
| US-6124278-A | COGNITION ACTIVATORS FOR LEARNING/MEMORY ENHANCEMENT AND TREATMENT OF BRAIN/PSYCHOLOGICAL DISORDERS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-09-26 | — | — | US | disclosed |
| WO-1999051240-A1 | ACYLBENZOXAZINES FOR ENHANCING SYNAPTIC RESPONSE(S) | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-10-14 | — | — | WO | disclosed |