Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12038994 | 0.98 | L3MBTL1 (0.50) | L3MBTL1MBTD1SMN1; SMN2HRH3CYP1A2 | |
| SCHEMBL12930425 | 0.83 | L3MBTL1 (0.54) | L3MBTL1MBTD1SMN1; SMN2HRH3CYP1A2 | |
| SCHEMBL21610873 | 0.80 | L3MBTL1 (0.55) | L3MBTL1MBTD1SMN1; SMN2HRH3SFRP1 | |
| SCHEMBL4710735 | 0.78 | L3MBTL1 (0.50) | L3MBTL1MBTD1SMN1; SMN2HRH3MAPK1 | |
| SCHEMBL12448142 | 0.74 | GRIA1 (0.55) | L3MBTL1MBTD1SMN1; SMN2HRH3RAD52 | |
| SCHEMBL27876126 | 0.73 | KDM4E (0.46) | L3MBTL1MBTD1SMN1; SMN2HRH3CYP1A2 | |
| SCHEMBL917669 | 0.72 | HRH3 (0.48) | L3MBTL1MBTD1SMN1; SMN2HRH3CYP1A2 | |
| SCHEMBL29229351 | 0.72 | GRIA1 (0.42) | SMN1; SMN2LMNA | |
| SCHEMBL25477820 | 0.72 | RAD52 (0.53) | L3MBTL1SMN1; SMN2HRH3CYP1A2MAPK1 | |
| SCHEMBL30331344 | 0.72 | FPR3 (0.49) | SMN1; SMN2HRH3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003082263-A1 | SULFAMIC ACIDS AS INHIBITORS OF HUMAN CYTOPLASMIC PROTEIN TYROSINE PHOSPHATASES | ONTOGEN CORPORATION (US) | 2003-10-09 | — | — | WO | disclosed |