Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7259478 | 0.90 | KDM4E (0.51) | KDM4EALDH1A1GAAHPGDSMN1; SMN2 | |
| SCHEMBL7263989 | 0.83 | KDM4E (0.44) | RAB9AKDM4EALDH1A1GAASMN1; SMN2 | |
| SCHEMBL7262910 | 0.79 | LMNA (0.44) | ALDH1A1GAASMN1; SMN2HSD17B10 | |
| SCHEMBL7263951 | 0.76 | — | — | |
| SCHEMBL7258099 | 0.76 | — | — | |
| SCHEMBL8152565 | 0.75 | — | — | |
| SCHEMBL7254850 | 0.74 | — | — | |
| SCHEMBL7259083 | 0.74 | — | — | |
| SCHEMBL8154422 | 0.74 | — | — | |
| SCHEMBL6780106 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003000664-A1 | URACIL DERIVATIVES AND THE USE THEREOF FOR TREATING BACTERIAL DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |