Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7258099 | 0.84 | — | — | |
| SCHEMBL7258716 | 0.83 | RAB9A (0.40) | KDM4EHSD17B10ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL8152565 | 0.80 | — | — | |
| SCHEMBL7257430 | 0.80 | NPC1 (0.43) | ALDH1A1NPC1RAB9AMAPTMEN1 | |
| SCHEMBL7254850 | 0.80 | — | — | |
| SCHEMBL7259083 | 0.79 | — | — | |
| SCHEMBL8154422 | 0.79 | — | — | |
| SCHEMBL6780106 | 0.78 | — | — | |
| SCHEMBL7262910 | 0.78 | LMNA (0.44) | HSD17B10ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL8154174 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003000664-A1 | URACIL DERIVATIVES AND THE USE THEREOF FOR TREATING BACTERIAL DISEASES | BAYER AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |