SCHEMBL725879

SCHEMBL725879

O=c1oc(=O)oc2c(Cl)cc(o1)c1c3cc(Cl)c(oc(=O)oc(=O)o3)c21

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
AHR P35869 17/20 0.40
KMO O15229 1/20 0.38
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL727207 0.94 AHR (0.41) AHRKMOMGAMGAASI
SCHEMBL9858230 0.70 AHR (0.41) AHR
SCHEMBL12878745 0.69 CA1 (0.34) GAATTR
SCHEMBL856949 0.69 MAOA (0.38) MGAMGAASIMGAM2
SCHEMBL9389992 0.67 NPC1 (0.34)
SCHEMBL1662244 0.66 MAPT (0.33) MGAMGAASIMGAM2
SCHEMBL8018963 0.64 MAOA (0.46) MGAMGAASIMGAM2
SCHEMBL5706548 0.64 MAPT (0.35)
SCHEMBL3885056 0.62 AHR (0.67) AHR
SCHEMBL8181568 0.62 AHR (0.33) AHRKMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1395627-B1 POLYIMIDE COMPOSITION HAVING IMPROVED PEEL STRENGTH DU PONT (US) 2006-11-02 EP claimed
WO-2021122715-A1 THERMOPLASTIC MOULDING COMPOSITION CONTAINING POLYALKYLENE TEREPHTHALATE BASF SE (DE) 2021-06-24 WO disclosed
EP-2714806-B1 THERMOPLASTIC MOULDING MATERIAL BASF SE (DE) 2015-07-08 EP disclosed
EP-2780393-A1 POLYMERIC MATERIAL, AND THE PRODUCTION AND USE THEREOF BASF SE (DE) 2014-09-24 EP disclosed
EP-2576650-B1 MATERIALS, PROCESS FOR PRODUCTION THEREOF AND COMPONENTS THEREFOR BASF SE (DE) 2014-05-14 EP disclosed
WO-2013072224-A1 POLYMERIC MATERIAL, AND THE PRODUCTION AND USE THEREOF BASF SE (DE) 2013-05-23 WO disclosed
EP-2576650-A1 MATERIALS, PROCESS FOR PRODUCTION THEREOF AND COMPONENTS THEREFOR BASF SE (DE) 2013-04-10 EP disclosed
WO-2012163680-A1 THERMOPLASTIC MOLDING COMPOUND BASF SE (DE) 2012-12-06 WO disclosed
WO-2011147723-A1 MATERIALS, PROCESS FOR PRODUCTION THEREOF AND COMPONENTS THEREFOR BASF SE (DE) 2011-12-01 WO disclosed